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A Phase 3, Randomized, Double-Blind Study of Pamrevlumab or Placebo in Combination With Either Gemcitabine Plus Nab-paclitaxel (G/NP) or FOLFIRINOX as Neoadjuvant Treatment in Patients With Locally Advanced, Unresectable Pancreatic Cancer

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Trial Profile

A Phase 3, Randomized, Double-Blind Study of Pamrevlumab or Placebo in Combination With Either Gemcitabine Plus Nab-paclitaxel (G/NP) or FOLFIRINOX as Neoadjuvant Treatment in Patients With Locally Advanced, Unresectable Pancreatic Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Nov 2024

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At a glance

  • Drugs Pamrevlumab (Primary) ; Fluorouracil; Folinic acid; Gemcitabine; Irinotecan; Oxaliplatin; Paclitaxel
  • Indications Adenocarcinoma; Pancreatic cancer; Pancreatic ductal carcinoma
  • Focus Registrational; Therapeutic Use
  • Acronyms LAPIS
  • Sponsors FibroGen

    • Most Recent Events

    • 26 Aug 2024 Status changed from active, no longer recruiting to completed.
    • 30 Jul 2024 Results published in a FibroGen media release,
    • 30 Jul 2024 According to a FibroGen media release, Primary endpoint (Overall Survival (OS)) has not been met.

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