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An Open-Label, Exploratory Study of the Safety and Preliminary Efficacy of Danicamtiv in Stable Ambulatory Participants With Primary Dilated Cardiomyopathy Due to Either MYH7 or TTN Variants or Other Causalities

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Trial Profile

An Open-Label, Exploratory Study of the Safety and Preliminary Efficacy of Danicamtiv in Stable Ambulatory Participants With Primary Dilated Cardiomyopathy Due to Either MYH7 or TTN Variants or Other Causalities

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 11 Nov 2025

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At a glance

  • Drugs Danicamtiv (Primary)
  • Indications Dilated cardiomyopathy
  • Focus Adverse reactions; Proof of concept
  • Sponsors Bristol-Myers Squibb; MyoKardia

Most Recent Events

  • 29 Sep 2025 According to Kardigan media release, the company announced that positive Phase 2a clinical trial data were presented in a late-breaking oral session at the Heart Failure Society of America (HFSA) Annual Scientific Meeting 2025 and simultaneously published in The Journal of the American College of Cardiology (JACC).
  • 29 Sep 2025 Results published in the Media Release
  • 26 Mar 2024 Status changed from recruiting to discontinued.

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