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A PHASE I DOSE ESCALATION AND EXPANDED COHORT STUDY OF PF 06821497 (MEVROMETOSTAT) IN THE TREATMENT OF ADULT PATIENTS WITH RELAPSED/REFRACTORY SMALL CELL LUNG CANCER (SCLC), CASTRATION RESISTANT PROSTATE CANCER (CRPC) AND FOLLICULAR LYMPHOMA (FL)

Trial Profile

A PHASE I DOSE ESCALATION AND EXPANDED COHORT STUDY OF PF 06821497 (MEVROMETOSTAT) IN THE TREATMENT OF ADULT PATIENTS WITH RELAPSED/REFRACTORY SMALL CELL LUNG CANCER (SCLC), CASTRATION RESISTANT PROSTATE CANCER (CRPC) AND FOLLICULAR LYMPHOMA (FL)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 18 Apr 2025

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At a glance

  • Drugs Enzalutamide (Primary) ; Mevrometostat (Primary) ; Carboplatin; Cisplatin; Etoposide
  • Indications Diffuse large B cell lymphoma; Follicular lymphoma; Prostate cancer; Small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Pfizer
  • Most Recent Events

    • 15 Apr 2025 Planned End Date changed from 9 Dec 2025 to 19 Mar 2026.
    • 15 Apr 2025 Planned primary completion date changed from 9 Dec 2025 to 19 Mar 2026.
    • 28 Jan 2025 According to an pfizer media release, data from this study will be presented at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium taking place February 13-15 in San Francisco, California.

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