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A Phase 1, Open-label, Single-dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Zanubrutinib (BGB-3111) in Subjects With Varying Degrees of Hepatic Impairment

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Trial Profile

A Phase 1, Open-label, Single-dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Zanubrutinib (BGB-3111) in Subjects With Varying Degrees of Hepatic Impairment

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Zanubrutinib (Primary)
  • Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Lupus nephritis; Lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; SARS-CoV-2 acute respiratory disease; Waldenstrom's macroglobulinaemia
  • Focus Pharmacokinetics
  • Sponsors BeiGene

    • Most Recent Events

    • 08 Mar 2019 Status changed from active, no longer recruiting to completed.
    • 07 Jun 2018 Status changed from not yet recruiting to active, no longer recruiting.
    • 25 May 2018 Planned initiation date changed from 1 Apr 2018 to 1 May 2018.

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