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Symphony-1: A Phase 1b/3 Double-Blind, Randomized, Active-Controlled, 3-Stage, Biomarker Adaptive Study Of Tazemetostat Or Placebo In Combination With Lenalidomide Plus Rituximab In Subjects With Relapsed/Refractory Follicular Lymphoma

Trial Profile

Symphony-1: A Phase 1b/3 Double-Blind, Randomized, Active-Controlled, 3-Stage, Biomarker Adaptive Study Of Tazemetostat Or Placebo In Combination With Lenalidomide Plus Rituximab In Subjects With Relapsed/Refractory Follicular Lymphoma

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 04 Dec 2024

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At a glance

  • Drugs Tazemetostat (Primary) ; Lenalidomide; Rituximab
  • Indications Follicular lymphoma
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms SYMPHONY-1
  • Sponsors Epizyme
  • Most Recent Events

    • 31 May 2024 Planned End Date changed from 27 Apr 2032 to 1 Mar 2029.
    • 31 May 2024 Planned primary completion date changed from 30 Sep 2029 to 1 Mar 2026.
    • 18 Apr 2024 Planned number of patients changed from 568 to 612.

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