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A Randomized, Double-Blind Phase 2/3 Study of Relatlimab Combined With Nivolumab Versus Nivolumab in Participants With Previously Untreated Metastatic or Unresectable Melanoma

Trial Profile

A Randomized, Double-Blind Phase 2/3 Study of Relatlimab Combined With Nivolumab Versus Nivolumab in Participants With Previously Untreated Metastatic or Unresectable Melanoma

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 19 Mar 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Nivolumab/relatlimab (Primary)
  • Indications Acral lentiginous melanoma; Malignant melanoma
  • Focus Registrational; Therapeutic Use
  • Acronyms RELATIVITY-047
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 17 Mar 2025 Planned End Date changed from 16 Dec 2025 to 15 Dec 2030.
    • 04 Jun 2024 Results (At database lock 19 Oct 2023) assessing safety and efficacy of Nivolumab plus relatlimab vs NIVO in previously untreated metastatic or unresectable melanoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 23 May 2024 According to Bristol Myers Squibb media release, the company announced the presentation of data across its oncology and hematology portfolio at the upcoming 2024 American Society of Clinical Oncology (ASCO) Annual Meeting and the European Hematology Association (EHA) 2024 Hybrid Congress.

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