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To assess whether administration of two doses of an oral, irreversible inhibitor of Brutons tyrosine kinase (BTK) (Ibrutinib) reduces allergic responses in food allergic subjects and eliminates IgE mediated basophil activation ex vivo

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Trial Profile

To assess whether administration of two doses of an oral, irreversible inhibitor of Brutons tyrosine kinase (BTK) (Ibrutinib) reduces allergic responses in food allergic subjects and eliminates IgE mediated basophil activation ex vivo

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Mar 2018

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At a glance

  • Drugs Ibrutinib (Primary)
  • Indications Food hypersensitivity
  • Focus Therapeutic Use

    • Most Recent Events

    • 23 Mar 2018 New trial record
    • 05 Mar 2018 Results presented at the 2018 Annual Meeting of the American Academy of Allergy, Asthma and Immunology

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