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A Phase 2 Study of Lisocabtagene Maraleucel (JCAR017) as Second-Line Therapy in Adult Patients With Aggressive B-cell NHL (017006)

Trial Profile

A Phase 2 Study of Lisocabtagene Maraleucel (JCAR017) as Second-Line Therapy in Adult Patients With Aggressive B-cell NHL (017006)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Dec 2023

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At a glance

  • Drugs Lisocabtagene-maraleucel (Primary) ; Cyclophosphamide; Fludarabine
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Non-Hodgkin's lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms PILOT; TRANSCEND-NHL-006
  • Sponsors Juno Therapeutics
  • Most Recent Events

    • 12 Dec 2023 Results to assess post infusion monitoring-related HCRU identify from pooled TRANSFORM and PILOT studies, presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 12 Dec 2023 Results of analysis assessing HCRU and costs for managing CRS and/or NEs after liso-cel administration among patients with R/R large B-cell lymphoma (LBCL) treated with liso-cel as 2L therapy in two clinical studies: TRANSFORM and PILOT presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 12 Dec 2023 Results of final analysis presented at the 65th American Society of Hematology Annual Meeting and Exposition
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