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Postoperative Adjuvant Radiochemotherapy (aRCH) With Cisplatin (C) Versus aRCH With C and Pembrolizumab (P) in Locally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC); Multicenter Randomized Phase II Study Within the German Interdisciplinary Study Group of German Cancer Society (IAG KHT); Pembro-Adjuvant-highRisk

Trial Profile

Postoperative Adjuvant Radiochemotherapy (aRCH) With Cisplatin (C) Versus aRCH With C and Pembrolizumab (P) in Locally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC); Multicenter Randomized Phase II Study Within the German Interdisciplinary Study Group of German Cancer Society (IAG KHT); Pembro-Adjuvant-highRisk

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Sep 2023

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At a glance

  • Drugs Pembrolizumab (Primary) ; Cisplatin
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms ADRISK
  • Most Recent Events

    • 05 Sep 2023 Planned End Date changed from 1 Aug 2024 to 1 Jan 2025.
    • 05 Sep 2023 Planned primary completion date changed from 1 Aug 2024 to 1 Jan 2025.
    • 13 Sep 2022 Trial design, presented at the 47th European Society for Medical Oncology Congress
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