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A Phase II, Open-label Pilot Study Evaluating the Safety and Activity of Liposomal Irinotecan in Combination With 5-FU and Oxaliplatin in Preoperative Treatment of Pancreatic Adenocarcinoma (NEO-Nal- IRI Study)

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A Phase II, Open-label Pilot Study Evaluating the Safety and Activity of Liposomal Irinotecan in Combination With 5-FU and Oxaliplatin in Preoperative Treatment of Pancreatic Adenocarcinoma (NEO-Nal- IRI Study)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 30 Jan 2025

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At a glance

  • Drugs Irinotecan (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms NEO-Nal- IRI Study

    • Most Recent Events

    • 27 Jan 2025 Planned End Date changed from 1 Dec 2024 to 1 Jul 2025.
    • 20 Jan 2024 Results assessing safety and activity of liposomal irinotecan (Nal-IRI) in combination with 5-FU and oxaliplatin (NALIRIFOX) in preoperative treatment of pancreatic adenocarcinoma presented at the 2024 Gastrointestinal Cancers Symposium
    • 01 Dec 2023 Study design discussed in an abstract published at 115th Annual Meeting of the American Association for Cancer Research

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