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An Investigator Initiated, Phase II Single-Center, Randomized, Open-Label, Prospective, Comparative Study To Determine The Efficacy, Safety, And Tolerability Of Ceftolozane-Tazobactam Plus Vancomycin, Linezolid Versus Standard Of Care Plus Vancomycin, Linezolid As Empiric Therapy In Febrile Neutropenic Adults With Cancer

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Trial Profile

An Investigator Initiated, Phase II Single-Center, Randomized, Open-Label, Prospective, Comparative Study To Determine The Efficacy, Safety, And Tolerability Of Ceftolozane-Tazobactam Plus Vancomycin, Linezolid Versus Standard Of Care Plus Vancomycin, Linezolid As Empiric Therapy In Febrile Neutropenic Adults With Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 18 May 2022

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At a glance

  • Drugs Ceftolozane/tazobactam (Primary) ; Cefepime; Linezolid; Meropenem; Piperacillin/tazobactam; Vancomycin
  • Indications Bacterial infections; Febrile neutropenia
  • Focus Therapeutic Use

    • Most Recent Events

    • 04 Mar 2022 Status changed from active, no longer recruiting to completed.
    • 01 Feb 2021 Planned End Date changed from 31 May 2021 to 31 May 2022.
    • 25 Oct 2020 Primary endpoint (Favorable Clinical Response at End of Inpatient Intravenous Therapy (EOIV)), has been met according to results presented at the IDWeek 2020
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