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Phase I/II Trial of Avelumab in Combination With Chemoradiation in the Treatment of Stage II/III Resectable Esophageal and Gastroesophageal Cancer

Trial Profile

Phase I/II Trial of Avelumab in Combination With Chemoradiation in the Treatment of Stage II/III Resectable Esophageal and Gastroesophageal Cancer

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 29 Jul 2024

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At a glance

  • Drugs Avelumab (Primary) ; Carboplatin (Primary) ; Paclitaxel (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Large cell carcinoma; Oesophageal cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 26 Jul 2024 Status changed from active, no longer recruiting to completed.
  • 07 Jun 2022 Enrollment was stopped after 16 patients in the expansion cohort due to accrual delays and changes in standard treatment
  • 07 Jun 2022 Results assessing safety and efficacy of avelumab with perioperative CRT in resectable esophageal and gastroesophageal junction cancer, presented at the 58th Annual Meeting of the American Society of Clinical Oncology.

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