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A Phase 1, Open-Label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Antineoplastic Activity of Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Trial Profile

A Phase 1, Open-Label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Antineoplastic Activity of Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Oct 2021

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At a glance

  • Drugs Sym-023 (Primary)
  • Indications Lymphoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Symphogen

Most Recent Events

  • 21 Sep 2020 Results of three phase1, first-in-human studies (NCT03311412, NCT03489369; NCT03489343) assessing effect Sym021, Sym022, and Sym023 alone and Sym021 in combination with either Sym022 or Sym023, presented at the 45th European Society for Medical Oncology Congress.
  • 08 Sep 2020 Status changed from active, no longer recruiting to completed.
  • 09 Jan 2020 Planned primary completion date changed from 1 Dec 2019 to 1 Jun 2020.

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