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Phase I, Open-label, Single Sequence, Two-Period Study to Evaluate the Effect of Tepotinib on P-gp by Investigating the PK of the P-gp Probe Substrate Dabigatran Etexilate in Healthy Subjects

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Trial Profile

Phase I, Open-label, Single Sequence, Two-Period Study to Evaluate the Effect of Tepotinib on P-gp by Investigating the PK of the P-gp Probe Substrate Dabigatran Etexilate in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 Aug 2023

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At a glance

  • Drugs Tepotinib (Primary) ; Dabigatran etexilate
  • Indications Liver cancer; Non-small cell lung cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Merck KGaA

    • Most Recent Events

    • 03 Aug 2023 Interventional Study Model changed to Crossover, Number of treatment arms changed to 2.
    • 10 Sep 2018 Status changed from recruiting to completed.
    • 16 Jul 2018 Planned End Date changed from 20 Jul 2018 to 6 Aug 2018.

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