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A Multicenter, Open-label Study to Evaluate the Safety and Efficacy of ICP-022 in Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL)

Trial Profile

A Multicenter, Open-label Study to Evaluate the Safety and Efficacy of ICP-022 in Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL)

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 Jan 2024

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At a glance

  • Drugs Orelabrutinib (Primary)
  • Indications Mantle-cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Sponsors InnoCare Pharma
  • Most Recent Events

    • 12 Dec 2023 Results assessing an updated analysis to indirectly compare the long-term efficacy between zanubrutinib (median follow up: 35.3 months) and orelabrutinib (median follow up: 23.8 months) in patients with R/R MCL, were presented at the 65th American Society of Hematology Annual Meeting and Exposition.
    • 08 Jul 2023 Results (NCT03206970 and NCT03494179) assessing Indirect comparisons of efficacy of zanubrutinib versus orelabrutinib in patients with relapsed or refractory small lymphocytic lymphoma or relapsed or refractory mantle cell lymphoma published in the Investigational New Drugs.
    • 02 Jun 2023 Planned End Date changed from 31 Dec 2022 to 31 Dec 2023.

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