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A Phase II, Randomized, Active-Controlled, Multi-Center Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Guided by Genomic Profiling Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site Who Have Received Three Cycles of Platinum Doublet Chemotherapy

Trial Profile

A Phase II, Randomized, Active-Controlled, Multi-Center Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Guided by Genomic Profiling Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site Who Have Received Three Cycles of Platinum Doublet Chemotherapy

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 19 Nov 2019

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At a glance

  • Drugs Alectinib (Primary) ; Atezolizumab (Primary) ; Bevacizumab (Primary) ; Cobimetinib (Primary) ; Entrectinib (Primary) ; Erlotinib (Primary) ; Ipatasertib (Primary) ; Olaparib (Primary) ; Pertuzumab (Primary) ; Trastuzumab (Primary) ; Vemurafenib (Primary) ; Vismodegib (Primary) ; Carboplatin; Cisplatin; Gemcitabine; Paclitaxel
  • Indications Cancer
  • Focus Therapeutic Use
  • Acronyms CUPISCO
  • Sponsors Roche
  • Most Recent Events

    • 23 Jan 2019 Planned End Date changed from 16 Apr 2022 to 25 Jun 2022.
    • 23 Jan 2019 Planned primary completion date changed from 16 Apr 2022 to 25 Jun 2021.
    • 18 Apr 2018 New trial record
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