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A Phase I Study of B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells in Combination With JSMD194, a Small Molecule Inhibitor of Gamma Secretase, in Patients With Relapsed or Persistent Multiple Myeloma

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Trial Profile

A Phase I Study of B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells in Combination With JSMD194, a Small Molecule Inhibitor of Gamma Secretase, in Patients With Relapsed or Persistent Multiple Myeloma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Apr 2019

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At a glance

  • Drugs CAR-BCMA-T-cell (Primary) ; Crenigacestat (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Multiple myeloma
  • Focus Adverse reactions

    • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 18 Jun 2018 Status changed from not yet recruiting to recruiting.
    • 23 Apr 2018 New trial record
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