Trial Profile

A Phase 3 pivotal trial PTI-428 in subjects on either Orkambi or Symdeko background therapy

Status: Planning

Phase of Trial: Phase III

Latest Information Update: 17 Jul 2025

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At a glance

Drugs Nesolicaftor (Primary)
Indications Cystic fibrosis
Focus Registrational; Therapeutic Use
Sponsors Kineta; Proteostasis Therapeutics; TuHURA Biosciences; Yumanity Therapeutics

Most Recent Events

30 Jun 2025 According to TuHURA Biosciences media release, Kineta has been acquired and merged into TuHURA Biosciences.
19 Dec 2022 According to a Kineta media release, Yumanity Therapeutics was merged with Kineta to form Kineta.
23 Apr 2018 New trial record

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