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A Randomized, Open-Label, Phase 1-2 Study of ASTX727 Low Dose (ASTX727 LD) Extended Schedule in Subjects With Lower Risk (IPSS Low or Intermediate-1) Myelodysplastic Syndromes (MDS)

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Trial Profile

A Randomized, Open-Label, Phase 1-2 Study of ASTX727 Low Dose (ASTX727 LD) Extended Schedule in Subjects With Lower Risk (IPSS Low or Intermediate-1) Myelodysplastic Syndromes (MDS)

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 May 2025

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At a glance

  • Drugs Cedazuridine/decitabine (Primary) ; Decitabine; Decitabine
  • Indications Myelodysplastic syndromes
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Astex Pharmaceuticals; Taiho Oncology

Most Recent Events

  • 02 Dec 2024 Planned End Date changed from 1 Dec 2024 to 1 Dec 2025.
  • 02 Dec 2024 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2025.
  • 31 Aug 2023 Planned End Date changed from 1 Jun 2023 to 1 Dec 2024.

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