Trial Profile

Phase II Study of Ibrutinib in Combination With Ixazomib in Patients With Waldenström Macroglobulinemia

Status: Discontinued

Phase of Trial: Phase II

Latest Information Update: 20 Feb 2026

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At a glance

Drugs Ibrutinib (Primary) ; Ixazomib (Primary)
Indications Waldenstrom's macroglobulinaemia
Focus Therapeutic Use

Most Recent Events

18 Sep 2025 Status changed from active, no longer recruiting to discontinued.
07 Feb 2025 Planned End Date changed from 1 May 2025 to 11 Mar 2026.
13 Dec 2022 Preliminary results assessing efficacy of ixazomib and ibrutinib in patients with newly diagnosed as well as relapsed/refractory waldenstrom macroglobulinemia, presented at the 64th American Society of Hematology Annual Meeting and Exposition.

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