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Open-label Extension Study with Tadekinig Alfa (r-hIL-18BP) to Monitor Safety and Tolerability in Patients with IL-18 Driven Monogenic Autoinflammatory Conditions: NLRC4 Mutation and XIAP Deficiency

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Trial Profile

Open-label Extension Study with Tadekinig Alfa (r-hIL-18BP) to Monitor Safety and Tolerability in Patients with IL-18 Driven Monogenic Autoinflammatory Conditions: NLRC4 Mutation and XIAP Deficiency

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 19 Mar 2025

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At a glance

  • Drugs Tadekinig alfa (Primary)
  • Indications Autoimmune disorders; Haemophagocytic lymphohistiocytosis
  • Focus Adverse reactions; Pharmacodynamics; Registrational
  • Sponsors AB2 Bio

    • Most Recent Events

    • 17 Mar 2025 Status changed from active, no longer recruiting to completed.
    • 31 Jul 2024 Planned End Date changed from 30 May 2024 to 30 Oct 2024.
    • 31 Jul 2024 Planned primary completion date changed from 30 Apr 2024 to 30 Sep 2024.

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