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An Open-label, First-in-human, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate, BAY2287411 Injection, in Patients With Solid Tumors Known to Express Mesothelin

Trial Profile

An Open-label, First-in-human, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate, BAY2287411 Injection, in Patients With Solid Tumors Known to Express Mesothelin

Recruiting
Phase of Trial: Phase I

Latest Information Update: 31 Jan 2019

At a glance

  • Drugs BAY-2287411 (Primary)
  • Indications Mesothelioma; Ovarian cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Bayer
  • Most Recent Events

    • 27 Dec 2018 Planned End Date changed from 20 Dec 2022 to 20 Feb 2023.
    • 26 Sep 2018 Planned number of patients changed from 42 to 228.
    • 26 Sep 2018 Planned End Date changed from 1 Jan 2021 to 20 Dec 2022.
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