Trial Profile

Phase I/II Study of Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 30 Jan 2025

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At a glance

Drugs Epacadostat (Primary) ; Capecitabine; Fluorouracil; Folinic acid; Oxaliplatin; Oxaliplatin
Indications Rectal cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

13 Nov 2024 FOLFOX chemotherapy added newly.
13 Nov 2024 Planned number of patients changed from 39 to 49.
10 Apr 2024 Results (n=17) assessing the safety of IDO1 inhibition when combined with neoadjuvant short-course radiation (SCRT) and chemotherapy with capecitabine and oxaliplatin presented at the 115th Annual Meeting of the American Association for Cancer Research

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