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A Phase 3b, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial of Linaclotide 290 μg Administered Orally for 12 Weeks Followed by a 4-week Randomized Withdrawal Period in Patients With Irritable Bowel Syndrome With Constipation

Trial Profile

A Phase 3b, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial of Linaclotide 290 μg Administered Orally for 12 Weeks Followed by a 4-week Randomized Withdrawal Period in Patients With Irritable Bowel Syndrome With Constipation

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 18 Jun 2019

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At a glance

  • Drugs Linaclotide (Primary)
  • Indications Constipation; Irritable bowel syndrome
  • Focus Therapeutic Use
  • Sponsors Ironwood Pharmaceuticals
  • Most Recent Events

    • 18 Jun 2019 According to an Ironwood Pharmaceuticals media release, additional data from this trial are expected to be shared at upcoming scientific meetings and via peer-reviewed publications.
    • 18 Jun 2019 Results presented in an Ironwood Pharmaceuticals Media Release.
    • 18 Jun 2019 According to an Ironwood Pharmaceuticals media release, primary endpoint (Change from Baseline in Abdominal Score (abdominal bloating, abdominal discomfort, and abdominal pain) at Each Week) has been met.
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