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Phase 1B Open-Label, Dose-Escalation and Dose-Expansion Study of APVO436 in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High-Grade Myelodysplastic Syndrome (MDS)

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Trial Profile

Phase 1B Open-Label, Dose-Escalation and Dose-Expansion Study of APVO436 in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High-Grade Myelodysplastic Syndrome (MDS)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Feb 2024

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At a glance

  • Drugs Mipletamig (Primary)
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions; First in man
  • Sponsors Aptevo Therapeutics

    • Most Recent Events

    • 13 Dec 2022 Interim Results (n=30, from the dose-expansion phase) assessing safety and tolerability of APVO436 in Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 09 Jun 2022 Results presented in an Aptevo Therapeutics Media Release.
    • 29 Mar 2022 Results presented in an Aptevo Therapeutics media release.

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