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A Multicenter, Open-label, Dose-escalating, Phase I Trial With GEM333, a CD33 Targeted Bispecific Antibody Engaging T-cells, in Relapsed or Refractory Acute Myeloid Leukemia

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Trial Profile

A Multicenter, Open-label, Dose-escalating, Phase I Trial With GEM333, a CD33 Targeted Bispecific Antibody Engaging T-cells, in Relapsed or Refractory Acute Myeloid Leukemia

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 30 Sep 2022

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At a glance

  • Drugs GEM-333 (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions; First in man
  • Sponsors AvenCell Europe
  • Most Recent Events

    • 28 Sep 2022 Status changed from active, no longer recruiting to discontinued. (The actions and measures to be taken to restart the trial could not be implemented which made the premature termination inevitability)
    • 08 Jul 2020 Status changed from recruiting to active, no longer recruiting.
    • 24 Jan 2020 Planned End Date changed from 31 Dec 2019 to 31 Dec 2020.

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