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A Double-Blind, Randomized, Placebo-Controlled, Single and Multiple Dose Study Evaluating the Safety, Tolerability, and Pharmacokinetics of AB-506, an HBV Capsid Inhibitor, in Healthy Subjects and HBV-DNA Positive Subjects with Chronic HBV Infection

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Trial Profile

A Double-Blind, Randomized, Placebo-Controlled, Single and Multiple Dose Study Evaluating the Safety, Tolerability, and Pharmacokinetics of AB-506, an HBV Capsid Inhibitor, in Healthy Subjects and HBV-DNA Positive Subjects with Chronic HBV Infection

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 15 Oct 2020

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At a glance

  • Drugs AB-506 (Primary) ; Tenofovir disoproxil fumarate
  • Indications Hepatitis B
  • Focus Adverse reactions; First in man
  • Sponsors Arbutus Biopharma

    • Most Recent Events

    • 29 Aug 2020 Results assessing HBV core variants observed in this trial presented at The International Liver Congress 2020
    • 06 Nov 2019 According to an Arbutus Biopharma media release, result will be presented at the American Association for the Study of Liver Diseases meeting.
    • 03 Oct 2019 Status changed from recruiting to discontinued, according to an Arbutus Biopharma media release.

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