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A Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab Given Concurrently With Platinum-based Chemoradiation Therapy in Patients With Locally Advanced, Unresectable NSCLC (Stage III) (PACIFIC2)

Trial Profile

A Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab Given Concurrently With Platinum-based Chemoradiation Therapy in Patients With Locally Advanced, Unresectable NSCLC (Stage III) (PACIFIC2)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 10 Apr 2025

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At a glance

  • Drugs Durvalumab (Primary) ; Carboplatin; Cisplatin; Etoposide; Paclitaxel; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms PACIFIC-2
  • Sponsors AstraZeneca; AstraZeneca AB

Most Recent Events

  • 12 Sep 2024 This trial has been completed in Hungary , according to European Clinical Trials Database record.
  • 11 Jan 2024 Planned End Date changed from 5 Sep 2024 to 31 Oct 2024.
  • 14 Nov 2023 Primary endpoint has not been met. (Progression-free survival (PFS)), according to an AstraZeneca Media Release.

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