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Randomized, Active-Comparison, Double-Blind, Phase 2 Study to Assess the Safety and Immunogenicity of Anthrax Vaccine Adsorbed (BioThrax) Without and With CPG 7909 Adjuvant (AV7909 Anthrax Vaccine), Using a Post-Exposure Prophylaxis Dosing Regimen in Adults 66 Years of Age or Older in Stable Health in Comparison to Adults 18-50 Years of Age in Stable Health

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Randomized, Active-Comparison, Double-Blind, Phase 2 Study to Assess the Safety and Immunogenicity of Anthrax Vaccine Adsorbed (BioThrax) Without and With CPG 7909 Adjuvant (AV7909 Anthrax Vaccine), Using a Post-Exposure Prophylaxis Dosing Regimen in Adults 66 Years of Age or Older in Stable Health in Comparison to Adults 18-50 Years of Age in Stable Health

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Anthrax vaccine (Primary) ; Anthrax vaccine adsorbed adjuvanted Emergent BioSolutions (Primary) ; Agatolimod
  • Indications Anthrax
  • Focus Adverse reactions; Pharmacodynamics
  • Acronyms B-SAFE

    • Most Recent Events

    • 28 Oct 2020 Results assessing the capacity of anthrax vaccines to generate a protective immune response in adults 66 years of age or older, published in the Vaccine
    • 13 Jul 2020 Status changed from active, no longer recruiting to completed.
    • 16 Jan 2020 Planned End Date changed from 13 Dec 2019 to 31 May 2020.

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