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A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Dose Cohort Study to Evaluate the Efficacy and Safety of Twelve Once-weekly Subcutaneous Doses of PB-119 in Drug-naive Subjects With Type 2 Diabetes Mellitus

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Trial Profile

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Dose Cohort Study to Evaluate the Efficacy and Safety of Twelve Once-weekly Subcutaneous Doses of PB-119 in Drug-naive Subjects With Type 2 Diabetes Mellitus

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Exenatide (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Sponsors PegBio

    • Most Recent Events

    • 09 Mar 2021 Results published in the Diabetologia
    • 16 Jun 2020 Primary endpoint (Change of glycosylated hemoglobin(HbA1c): all PB119 groups compared to placebo) has been met, according to results presented at the 80th Annual Scientific Sessions of the American Diabetes Association.
    • 16 Jun 2020 Results assessing the efficacy and safety of PB119 monotherapy in Chinese patients with T2DM, were presented at the 80th Annual Scientific Sessions of the American Diabetes Association.
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