Trial Profile

A Phase 1a/1b Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 15 Jul 2025

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At a glance

Drugs INCB-81776 (Primary) ; Retifanlimab (Primary)
Indications Acute myeloid leukaemia; Adenocarcinoma; Advanced breast cancer; Gastric cancer; Head and neck cancer; Liver cancer; Malignant melanoma; Non-small cell lung cancer; Renal cell carcinoma; Sarcoma; Soft tissue sarcoma; Solid tumours; Squamous cell cancer; Triple negative breast cancer; Urogenital cancer
Focus Adverse reactions
Sponsors Incyte Corporation

Most Recent Events

23 May 2025 Planned End Date changed from 1 Apr 2025 to 20 Sep 2025.
23 May 2025 Planned primary completion date changed from 1 Apr 2025 to 20 Sep 2025.
19 Dec 2024 Planned End Date changed from 31 Dec 2024 to 1 Apr 2025.

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