Trial Profile

A Phase 1 Study to Evaluate the Safety and Tolerability of AB680 Combination Therapy in Participants With Gastrointestinal Malignancies

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 06 Jun 2025

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At a glance

Drugs Gemcitabine (Primary) ; Paclitaxel (Primary) ; Quemliclustat (Primary) ; Zimberelimab (Primary)
Indications Adenocarcinoma; Gastrointestinal cancer; Pancreatic cancer
Focus Adverse reactions
Acronyms ARC-8
Sponsors Arcus Biosciences

Most Recent Events

31 May 2025 Study arms increased from 6 to 7. Study design changed from non-randomization to randomization.
08 May 2025 Status changed from recruiting to active, no longer recruiting.
23 May 2024 Planned number of patients changed from 211 to 195.

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