A Phase 3, Randomized Study of Zanubrutinib (BGB-3111) Compared With Ibrutinib in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Latest Information Update: 02 Apr 2025
At a glance
- Drugs Zanubrutinib (Primary) ; Ibrutinib
- Indications Chronic lymphocytic leukaemia
- Focus Registrational; Therapeutic Use
- Acronyms ALPINE
- Sponsors BeiGene
Most Recent Events
- 01 Mar 2025 Results(n=200) comparing the safety profiles of Ibrutinib and Zanubrutinib, in patients with chronic lymphocytic leukemia (CLL), published in the Hematological Oncology
- 01 Oct 2024 Results from the subgroup of Chinese patients, published in the Annals of Hematology.
- 24 May 2024 According to a BeiGene Media Release, the presentation of a network meta-analysis evaluating the relative efficacy of available treatments for patients with high-risk relapsed/refractory (R/R) CLL from clinical trials ALPINE, ELEVATE-RR and ASCEND will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, May 31 - June 4, 2024.