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An International Multicentre, Open-Label First in Human Phase I/II Study to Evaluate the Safety, Tolerability, Biodistribution and Antitumour Activity of 177Lu-3BP-227 for the Treatment of Subjects With Solid Tumours Expressing Neurotensin Receptor 1

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Trial Profile

An International Multicentre, Open-Label First in Human Phase I/II Study to Evaluate the Safety, Tolerability, Biodistribution and Antitumour Activity of 177Lu-3BP-227 for the Treatment of Subjects With Solid Tumours Expressing Neurotensin Receptor 1

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 18 Dec 2023

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At a glance

  • Drugs Zalsenertant-tetraxetan (Primary)
  • Indications Adenocarcinoma; Colorectal cancer; Ewing's sarcoma; Gastric cancer; Gastrointestinal stromal tumours; Head and neck cancer; Pancreatic cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Ipsen

    • Most Recent Events

    • 02 Jun 2021 Status changed from recruiting to discontinued due to agreement to transfer rights for IPN01087 to an external partner, not due to safety concerns
    • 21 Mar 2021 This trial has been completed in Belgium, according to European Clinical Trials Database record.
    • 23 Feb 2021 Planned End Date changed from 3 Aug 2026 to 3 Aug 2022.
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