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A Phase 1 Study of an Autologous ACTR T Cell Product in Combination With Trastuzumab, a Monoclonal Antibody, in Subjects With HER2-Positive Advanced Malignancies

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Trial Profile

A Phase 1 Study of an Autologous ACTR T Cell Product in Combination With Trastuzumab, a Monoclonal Antibody, in Subjects With HER2-Positive Advanced Malignancies

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs ACTR707 (Primary) ; Trastuzumab (Primary)
  • Indications Advanced breast cancer; Gastric cancer; Solid tumours
  • Focus Adverse reactions
  • Sponsors Cogent Biosciences

    • Most Recent Events

    • 02 Mar 2020 Status changed from recruiting to discontinued, according to an Unum Therapeutics media release.
    • 04 Nov 2019 According to an Unum Therapeutics media release, fives clinical sites are active in this study. The company expects to report preliminary data from this study from first cohort patients by the end of this year and expects data from the multiple dose cohort in 2020.
    • 28 Mar 2019 According to an Unum Therapeutics media release, compnay plans to report initial clinical data from the ongoing dose escalation at the end of 2019.
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