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Impact of the Combination of Durvalumab (MEDI4736) Plus Olaparib (AZD2281) Administered Prior to Surgery in the Molecular Profile of Resectable Urothelial Bladder Cancer

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Trial Profile

Impact of the Combination of Durvalumab (MEDI4736) Plus Olaparib (AZD2281) Administered Prior to Surgery in the Molecular Profile of Resectable Urothelial Bladder Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 31 Mar 2022

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At a glance

  • Drugs Durvalumab (Primary) ; Olaparib (Primary)
  • Indications Bladder cancer; Carcinoma; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms NEODURVARIB

    • Most Recent Events

    • 19 Feb 2022 Results evaluating the basal molecular profiles and their evolution under treatment with this combination, presented at the 2022 Genitourinary Cancers Symposium
    • 21 Sep 2020 Results assessing efficacy and safety of neoadjuvant combination of durvalumab plus olaparib in resectable urothelial bladder cancer, presented at the 45th European Society for Medical Oncology Congress
    • 03 Apr 2020 Status changed from recruiting to completed.
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