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Two-part, Double-blind, Placebo-controlled, Randomized, Parallel-group Study: (Part 1) in Healthy Male Subjects to Assess Safety and Tolerability of Ascending Repeated Oral Doses of BAY1902607 Including Its Effect on the Pharmacokinetics of a Sub-therapeutic Dose of Midazolam (MDZ), Followed by (Part 2) a Two-way Crossover Administration of Four Different Doses of BAY1902607 in Patients With Refractory Chronic Cough to Assess Safety, Tolerability and Efficacy for Proof of Concept

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Two-part, Double-blind, Placebo-controlled, Randomized, Parallel-group Study: (Part 1) in Healthy Male Subjects to Assess Safety and Tolerability of Ascending Repeated Oral Doses of BAY1902607 Including Its Effect on the Pharmacokinetics of a Sub-therapeutic Dose of Midazolam (MDZ), Followed by (Part 2) a Two-way Crossover Administration of Four Different Doses of BAY1902607 in Patients With Refractory Chronic Cough to Assess Safety, Tolerability and Efficacy for Proof of Concept

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs BAY 1902607 (Primary) ; Midazolam (Primary)
  • Indications Cough
  • Focus Adverse reactions; Pharmacokinetics; Proof of concept; Therapeutic Use
  • Sponsors Bayer

    • Most Recent Events

    • 07 Nov 2019 Status changed from active, no longer recruiting to completed.
    • 20 Aug 2019 Planned End Date changed from 18 Oct 2019 to 24 Oct 2019.
    • 22 Jul 2019 Status changed from recruiting to active, no longer recruiting.

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