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Phase 2, Open-Label Safety and Efficacy Study of Telisotuzumab Vedotin (ABBV-399) in Subjects With Previously Treated c-Met+ Non-Small Cell Lung Cancer

Trial Profile

Phase 2, Open-Label Safety and Efficacy Study of Telisotuzumab Vedotin (ABBV-399) in Subjects With Previously Treated c-Met+ Non-Small Cell Lung Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 29 May 2025

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At a glance

  • Drugs Telisotuzumab vedotin (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms LUMINOSITY
  • Sponsors AbbVie; AbbVie Germany

Most Recent Events

  • 27 May 2025 According to AbbVie media release, data from this trial will be presented at American Society of Clinical Oncology (ASCO) Annual Meeting.
  • 14 May 2025 According to an AbbVie media release, based on the data from this study, the company announced that EMRELIS (telisotuzumab vedotin-tllv) has been granted accelerated approval by the U.S. Food and Drug Administration (FDA) for the treatment of adult patients with locally advanced or metastatic, non-squamous NSCLC with high c-Met protein overexpression (OE) who have received a prior systemic therapy.
  • 14 May 2025 Results presented in an AbbVie media release.

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