Trial Profile

A Phase I/II Trial of Cabozantinib in Combination With Durvalumab (MEDI4736) With or Without Tremelimumab in Patients With Advanced Gastroesophageal Cancer and Other Gastrointestinal (GI) Malignancies (CAMILLA)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 29 Jan 2026

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At a glance

Drugs Cabozantinib (Primary) ; Durvalumab (Primary) ; Tremelimumab (Primary)
Indications Adenocarcinoma; Colorectal cancer; Gastric cancer; Gastrointestinal cancer; Liver cancer; Oesophageal cancer
Focus Adverse reactions; Therapeutic Use
Acronyms CAMILLA

21 Jan 2026 Planned End Date changed from 31 Jan 2028 to 30 Jun 2029.
21 Jan 2026 Planned primary completion date changed from 31 Jan 2027 to 30 Jun 2028.
14 Jan 2025 Planned End Date changed from 30 Nov 2027 to 31 Jan 2028.

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