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A phase Ib/II study evaluating safety and efficacy of NKTR-214 in combination with entinostat in patients with metastatic melanoma who have previously progressed on treatment with an anti-PD-1 (programmed death receptor-1) agent

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Trial Profile

A phase Ib/II study evaluating safety and efficacy of NKTR-214 in combination with entinostat in patients with metastatic melanoma who have previously progressed on treatment with an anti-PD-1 (programmed death receptor-1) agent

Status: Planning
Phase of Trial: Phase I/II

Latest Information Update: 16 Nov 2018

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At a glance

  • Drugs Bempegaldesleukin (Primary) ; Entinostat (Primary)
  • Indications Malignant melanoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ENCORE 606
  • Sponsors Syndax Pharmaceuticals

    • Most Recent Events

    • 05 Nov 2018 According to a Syndax Pharmaceuticals media release, this trial is expected to begin enrolling patients in the second quarter of 2019.
    • 07 Aug 2018 According to a Syndax Pharmaceuticals media release, this trial is expected to begin enrolling patients in the first half of 2019.
    • 05 Jun 2018 New trial record

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