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A Phase 1 First-In-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia

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Trial Profile

A Phase 1 First-In-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 16 Oct 2024

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At a glance

  • Drugs Emirodatamab (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions; First in man
  • Sponsors Amgen

Most Recent Events

  • 28 Feb 2023 Status changed from recruiting to discontinued.
  • 21 Nov 2022 Planned End Date changed from 5 May 2027 to 13 May 2025.
  • 21 Nov 2022 Planned primary completion date changed from 5 May 2027 to 13 May 2025.

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