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A Phase I, Open-Label Study to Investigate the Tolerability and Safety of IBI310 Alone or in Combination With Sintilimab in the Treatment of Patients With Advanced Solid Tumors

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Trial Profile

A Phase I, Open-Label Study to Investigate the Tolerability and Safety of IBI310 Alone or in Combination With Sintilimab in the Treatment of Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 01 Mar 2023

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At a glance

  • Drugs Ipilimumab (Primary) ; Sintilimab (Primary)
  • Indications Acral lentiginous melanoma; Malignant melanoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Innovent Biologics

    • Most Recent Events

    • 21 Sep 2021 Updated results (n=44; As of April 14, 2021) assessing safety and efficacy of IBI310 alone or in combination with sintilimab in patients with advanced melanoma, presented at the 46th European Society for Medical Oncology Congress.
    • 29 Aug 2021 According to an Innovent Biologics media release, data will be presented at the European Society for Medical Oncology (ESMO) Virtual Congress 2021.
    • 02 Jun 2020 According to an Innovent Biologics media release, preliminary results (as of 12th Nov 2019, n=10 in Phase 1a study and n=17 subjects in Phase 1b study) were announced in the form of online publication at the 56th American Society of Clinical Oncology (ASCO) Annual Meeting. (Online publication, Abstract # 302489).
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