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The effects of sacubitril/valsartan compared to valsartan on left ventricular remodelling in patients with asymptomatic left ventricular systolic dysfunction after myocardial infarction: a randomised, double-blinded, active-comparator, cardiac-MR based trial.

Trial Profile

The effects of sacubitril/valsartan compared to valsartan on left ventricular remodelling in patients with asymptomatic left ventricular systolic dysfunction after myocardial infarction: a randomised, double-blinded, active-comparator, cardiac-MR based trial.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 May 2023

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At a glance

  • Drugs Sacubitril/valsartan (Primary) ; Valsartan
  • Indications Heart failure; Left ventricular dysfunction; Myocardial infarction
  • Focus Proof of concept; Therapeutic Use
  • Acronyms RECOVER-LV
  • Most Recent Events

    • 13 May 2021 Primary endpoint (Left ventricular end systolic volume) baseline to 52-weeks has not been met. according to the results published in the Circulation.
    • 13 May 2021 Results assessing the comparison of sacubitril/valsartan with valsartan in patients with myocardial infarction (MI) and asymptomatic left ventricular systolic dysfunction (LVEF), published in the Circulation.
    • 10 Aug 2020 Status changed from active, no longer recruiting to completed.
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