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A Phase IIIb Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis

Trial Profile

A Phase IIIb Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 02 Jun 2026

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At a glance

  • Drugs Ocrelizumab (Primary)
  • Indications Multiple sclerosis
  • Focus Registrational; Therapeutic Use
  • Acronyms O'HAND; ORATORIO-HAND
  • Sponsors Roche

Most Recent Events

  • 24 Sep 2025 According to a Genentech media release, data from this study will be presented as on oral presentation at the at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) in Barcelona, Spain (September 24-26 )
  • 24 Sep 2025 Results published in the Media Release
  • 27 Dec 2024 Status changed from recruiting to active, no longer recruiting.

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