Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell Cancers
Latest Information Update: 16 May 2025
At a glance
- Drugs Bintrafusp alfa (Primary) ; Temozolomide (Primary) ; Topotecan (Primary) ; Antihistamines; Dexamethasone; Diphenhydramine; Epinephrine; Paracetamol
- Indications Small cell lung cancer
- Focus Therapeutic Use
Most Recent Events
- 09 May 2025 Protocol was amended to add a safety endpoint as the primary endpoint and addition of drugs like Epinephrine, Dexamethasone, Diphenhydramine, Antihistamines, Acetaminophen in the treatment arms.
- 09 May 2025 Status changed from active, no longer recruiting to completed.
- 06 Mar 2025 Status changed from recruiting to active, no longer recruiting.