Trial Profile

Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell Cancers

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 16 May 2025

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At a glance

Drugs Bintrafusp alfa (Primary) ; Temozolomide (Primary) ; Topotecan (Primary) ; Antihistamines; Dexamethasone; Diphenhydramine; Epinephrine; Paracetamol
Indications Small cell lung cancer
Focus Therapeutic Use

Most Recent Events

09 May 2025 Protocol was amended to add a safety endpoint as the primary endpoint and addition of drugs like Epinephrine, Dexamethasone, Diphenhydramine, Antihistamines, Acetaminophen in the treatment arms.
09 May 2025 Status changed from active, no longer recruiting to completed.
06 Mar 2025 Status changed from recruiting to active, no longer recruiting.

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