Trial Profile

Modified FOLFOX Plus/Minus Nivolumab and Ipilimumab vs. FLOT Plus Nivolumab in Patients With Previously Untreated Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction - A Randomized Phase 2 Trial.

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 17 Jan 2025

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At a glance

Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Ramucirumab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
Focus Therapeutic Use
Acronyms MOONLIGHT

09 Aug 2024 Status changed from active, no longer recruiting to completed.
06 May 2024 Results retrospectively analyzing efficacy of ramucirumab combination chemotherapy as second-line treatment , published in the International Journal of Cancer
24 Jul 2023 Planned End Date changed from 1 Sep 2023 to 1 Mar 2024.

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