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Immunogenicity, Reactogenicity and Safety of Two Formulations of GSK Biologicals' Meningococcal ACWY Conjugate Vaccine (GSK3536820A and Menveo) in Healthy Adults 18 to 40 Years of Age

Trial Profile

Immunogenicity, Reactogenicity and Safety of Two Formulations of GSK Biologicals' Meningococcal ACWY Conjugate Vaccine (GSK3536820A and Menveo) in Healthy Adults 18 to 40 Years of Age

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 15 Nov 2022

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At a glance

  • Drugs Meningococcal vaccine groups A C Y W-135 conjugate (Primary) ; Meningococcal vaccine groups A C Y W-135 conjugate
  • Indications Meningococcal group A infections; Meningococcal group C infections; Meningococcal group W-135 infections; Meningococcal group Y infections; Meningococcal infections
  • Focus Pharmacodynamics
  • Acronyms MENACWY CONJ-032_V59_71
  • Sponsors GlaxoSmithKline; GSK
  • Most Recent Events

    • 11 Nov 2022 Results (n=2669) of a pooled post analysis from two clinical studies (NCT03652610 and NCT03433482) using safety data from participants aged 10-40 years who received one dose of either liquid MenACWY-CRM or licensed MenACWY-CRM published in the Drug Safety
    • 08 Oct 2021 Primary endpoint (Human Serum Bactericidal Activity (hSBA) Geometric Mean Titers (GMTs) against N. meningitidis serogroup A for each vaccine group and between-groups ratios.) has been met as per results published in the Vaccine
    • 08 Oct 2021 Results published in the Vaccine
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