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NANT Colorectal Cancer (CRC) Vaccine: A Phase 1b/2 Trial of the NANT CRC Vaccine vs Regorafenib in Subjects With Metastatic CRC Who Have Been Previously Treated With Standard-of-Care Therapy

Trial Profile

NANT Colorectal Cancer (CRC) Vaccine: A Phase 1b/2 Trial of the NANT CRC Vaccine vs Regorafenib in Subjects With Metastatic CRC Who Have Been Previously Treated With Standard-of-Care Therapy

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 May 2019

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At a glance

  • Drugs Aldoxorubicin (Primary) ; ALT 803 (Primary) ; Avelumab (Primary) ; Brachyury peptide vaccine (Primary) ; Capecitabine (Primary) ; CD16 and interleukin 2 expressing natural killer cells-NantKwest (Primary) ; Cetuximab (Primary) ; Cyclophosphamide (Primary) ; ETBX 011 (Primary) ; ETBX 021 (Primary) ; ETBX-051 (Primary) ; ETBX-061 (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; GI 4000 (Primary) ; GI 6207 (Primary) ; Oxaliplatin (Primary) ; Paclitaxel (Primary) ; Regorafenib (Primary) ; Trastuzumab (Primary)
  • Indications Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors NantKwest
  • Most Recent Events

    • 15 May 2019 Status changed from recruiting to active, no longer recruiting.
    • 14 Jan 2019 According to a CytRx Corporation media release, aldoxorubicin licensee NantCell, Inc., a private subsidiary of NantWorks, LLC, has dosed the first patient in the phase 1b portion of this phase 1b/2 trial.
    • 28 Jun 2018 New trial record
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