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A Phase 3, Randomized, Double-blind, Active Comparator-controlled, Multicenter Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Recipients of Allogeneic Hematopoietic Stem Cell Transplant (PNEU-STEM)

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Trial Profile

A Phase 3, Randomized, Double-blind, Active Comparator-controlled, Multicenter Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Recipients of Allogeneic Hematopoietic Stem Cell Transplant (PNEU-STEM)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 13 Sep 2023

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At a glance

  • Drugs V 114 (Primary) ; Aluminium phosphate; Pneumococcal 13-valent CRM197 vaccine conjugate; Pneumococcal vaccine
  • Indications Pneumococcal infections
  • Focus Adverse reactions; Pharmacodynamics; Registrational
  • Acronyms PNEU-STEM
  • Sponsors Merck Sharp & Dohme Corp.

    • Most Recent Events

    • 20 Jun 2023 Results evaluating the safety and immunogenicity of V114, when given to allo-HCT recipients, published in the Clinical Infectious Diseases
    • 12 Nov 2021 Status changed from active, no longer recruiting to completed.
    • 16 Sep 2021 This trial has been completed in Belgium, according to European Clinical Trials Database record.

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