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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Voxelotor (GBT440) in Pediatric Participants With Sickle Cell Disease (HOPE Kids 2)

Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Voxelotor (GBT440) in Pediatric Participants With Sickle Cell Disease (HOPE Kids 2)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 21 Jan 2024

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At a glance

  • Drugs Voxelotor (Primary)
  • Indications Sickle cell anaemia
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms HOPE Kids 2
  • Sponsors Global Blood Therapeutics
  • Most Recent Events

    • 12 Dec 2023 Information of implementation of a standardized TCD screening protocol, presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 19 Jul 2023 Planned End Date changed from 1 Mar 2025 to 28 Jan 2025.
    • 19 Jul 2023 Planned primary completion date changed from 1 Mar 2025 to 5 Sep 2023.
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